Live Geos: https://partners.subjectwell.com/publishers/geos_report/2710209c-64c3-41be-b7c0-1add158aff11 Gender: All Ages: 18+ Study Description: This study is testing an investigational combination of two oral study medications in adults with chronic kidney disease (CKD) and high blood pressure. Participants will receive either an FDA-approved medication plus an investigational medication or placebo for 2 years. During the 2-year study treatment period, participants will complete 10 study visits. After the study treatment period, participants will have 2 visits after a 6-week follow-up period. Eligibility for the study will be determined by the study doctor following one or more in-person screening visits to the clinic. Study-related procedures and study medication will be provided at no cost. Qualifications: - Cannot have had dialysis in the last 3 months - Must be taking medication to lower your blood pressure, but blood pressure must still be high - Cannot have had a stroke, mini stroke (TIA), heart attack or been hospitalized for heart failure in the last 3 months - Cannot be currently pregnant or planning to become pregnant in the next 2 years - Cannot have type 1 diabetes

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