Ages: 18+ Gender: All Compensation: Participants who qualify for the study will receive trial-related procedures and study medication at no cost. Additionally, travel costs may be reimbursed, the site will discuss this with you. Study Description: The purpose of this clinical study is to see how effective an investigational topical medication is at helping to treat nerve pain after a surgical procedure - also known as chronic post-surgical neuropathic pain. Post-operative nerve pain is common after many different operations and is normally located around the incision area. You may be asked to attend a screening visit to determine if you are eligible to enroll in the study. If enrolled, you will receive either the topical medication being tested in this study (which is currently on the market for use in other indications), or a low dose medication (which looks like the study medication but contains a much lower concentration of the active medication) that is currently not on the market. Both options are an adhesive wearable patch that would be applied to your skin for 60 min at different timepoints during the study. Your total participation will last approximately 10 months and you will be asked to attend several in person visits over the course of the study. During these visits, you will complete various diagnostic and laboratory tests. The medical office conducting the study will be able to provide you with more information about the study requirements. Participants who qualify for the study will receive trial-related procedures and study medication at no cost. Additionally, travel costs may be reimbursed, the site will discuss this with you. - Pain cannot be result of an amputation surgery, back-surgery due to back-pain, or surgery due to nerve compression repair - Pain symptoms must be from the last 6 months - 5 years - Pain scale from be 4 out of 10 - Can be taking opioid medication to manage pain, but study will require you to stop - Cannot currently be part of a lawsuit due to chronic pain or disability

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