Geo: US, ZA Only Traffic: Email, Social, Display/ Native Ages: 18+ Gender: Any Study Description: The purpose of this clinical study is to see how effective an investigational medication is at helping to treat adults with moderately to severely active Ulcerative Colitis (UC). The study medication is currently FDA approved to treat several inflammatory conditions and is being explored as a new therapy option for UC patients. You may be asked to attend a screening visit and complete a screening endoscopy to determine if you are eligible to enroll in the study. If enrolled, you will receive either the medication being tested in this study or a placebo which will be self-administered as an injection, once a week, for one year. Your total participation will last approximately 16 months and you will be asked to attend 6 doctor’s visits. During these visits, you will complete various diagnostic and laboratory tests. Participants who qualify for the study will receive trial-related procedures and study medication at no cost and may be compensated for time and travel. The doctor’s office conducting the study will be able to provide you with more information about the study requirements. Qualifications: - Must be diagnosed with UC for 3 months or longer and confirmed with an endoscopy procedure (such as a flexible sigmoidoscopy or colonoscopy) - Must be currently experiencing symptoms of UC such as frequent stools and rectal bleeding - Currently taking prescription medication for your Ulcerative Colitis (common examples may include oral corticosteroids, 5-ASA compounds, or medications that stimulate or suppress the immune system) - Cannot have ever taken dupliumab (Dupixent) or Rituxan (rituximab) or Campath (alemtuzumab) - Cannot also be diagnosed with lupus, rheumatoid arthritis, or kidney disease that requires dialysis - Cannot have ever been diagnosed with short bowel symdrome or crohn's disease

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