LIVE GEOS (ALWAYS UP TO DATE) https://partners.subjectwell.com/publishers/geos_report/c8c8526c-2e61-44ab-9c82-e8c54d82c67b Age Range: 18+ Gender: Any Study Description: Periodically, individuals with gout have a sudden onset of symptoms, or a “flare,” characterized by severe pain, joint swelling, redness, and/or warmth in one or more joints. You have been referred here to be considered for participation in a clinical research study because you have gout or you have experienced symptoms of a gout flare in the past. Gout flares often start suddenly at night, and the intense pain may be bad enough to wake you up. Gout flares usually occur in one joint and can be triggered by certain foods or medications, alcohol intake, physical trauma, or certain illnesses. This research study is looking to see if an investigational drug (dapansutrile) can potentially reduce inflammation, joint pain, and other joint symptoms (such as tenderness and swelling) and if it is safe in adults currently experiencing a gout flare. You may be eligible to participate in the study immediately if you are currently having active symptoms of a gout flare, including warm, swollen, and/or painful joints (most commonly in the big toe). Even if you are not currently experiencing symptoms of a gout flare, you may still qualify to join a Virtual Waiting Room until the next time you develop active symptoms of a flare. Qualifications: - Must have gout diagnosis - Cannot be currently suffering from any other type of inflammatory arthritis or joint pain (instead of, or in addition to, gout), including: - Rheumatoid Arthritis - Lyme Disease - Lupus - Psoriatic Arthritis - Cannot have tophi associated with your gout (Tophi are visible bumps under the skin made of hardened deposits of uric acid crystals that develop around joints.)

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